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We consistently discovered that the population of dividing astrocytes was significantly smaller on the facet in which N-CAM or one of the N-CAM-related molecules was infused than on the other facet. The inhibition was best in the cortical lesion sites (approximately 50%) and was less pronounced within the hippocampus (approximately 25%) and striatum (approximately 20%). Two weeks after the lesion, the cerebral cortical sites infused with N-CAM continued to exhibit a considerably smaller inhabitants of dividing astrocytes than the sites on the other facet.
Menon VK, Landerholm TE. Intralesion injection of primary fibroblast development issue alters glial reactivity to neural trauma. Hemperly JJ, Murray BA, Edelman GM, Cunningham BA. Sequence of a cDNA clone encoding the polysialic acid-rich and cytoplasmic domains of the neural cell adhesion molecule N-CAM. Barrett CP, Donati EJ, Guth L. Differences between adult and neonatal rats in their astroglial response to spinal damage. March seventeenth – Male & female Osprey arrived at Round Swamp/Great Creek nest platform just south of the Zeek’s Bait Shop.