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We consistently discovered that the population of dividing astrocytes was significantly smaller on the facet in which N-CAM or one of the N-CAM-related molecules was infused than on the other facet. The inhibition was best in the cortical lesion sites (approximately 50%) and was less pronounced within the hippocampus (approximately 25%) and striatum (approximately 20%). Two weeks after the lesion, the cerebral cortical sites infused with N-CAM continued to exhibit a considerably smaller inhabitants of dividing astrocytes than the sites on the other facet.

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